Abstract
The talk starts with a reference to artificial and human intelligence. The issues of augmented humanity , nootropics and ingestibles are then introduced . The presentation then covers areas like cognitive neuroscience , neuromorphic computing and brain imaging . The discussion then follows into brain-computer interfaces , nanobots , mind machine and thought-controlled computing . The presentation ends by tackling conceptualisations like singularity , cyborgs, transhumans , post-humans and humachine .
Biography
Professor Luiz Moutinho (BA, MA, PhD, MAE, FCIM) is Visiting Professor of Marketing at Suffolk Business School, Faculty of Arts, Business and Applied Social Science, Univ. of Suffolk, Ipswich, England, UK, and at The Marketing School, Portugal, and Adjunct Professor of Marketing, GSB, FBE, University of the South Pacific, Suva, Fiji. In 2020 he was elected as the member of The Academia Europaea. In 2017 he received a degree of Prof. Honoris Causa from the Univ. of Tourism and Management Skopje, North Macedonia. During 2015 - 2017 he was professor of BioMarketing and Futures Research at the DCU Business School, Dublin City University, Ireland. This was the first Chair in the world on both domains - BioMarketing and Futures Research. Previously, and for 20 years, he had been appointed as the Foundation Chair of Marketing at the Adam Smith Business School, University of Glasgow, Scotland. He completed his PhD at the University of Sheffield in 1982. He has been a Full Professor for 34 years and held posts at Cardiff Business School, University of Wales College of Cardiff, Cleveland State University, Ohio, USA, Northern Arizona University, USA and California State University, USA. He has held Visiting Professorship positions at numerous universities in China, Lithuania, Austria, New Zealand, Denmark, Slovenia, Portugal, Hungary, Taiwan, Brazil, Colombia, Fiji and Cyprus. Between 1987 and 1989 he was the director of the Doctoral Programmes at the Confederation of Scottish Business Schools and at the Cardiff Business School between 1993 and 1996. He was director of the Doctoral Programme in Management at the University of Glasgow between 1996 and 2004. Professor Moutinho is the Founding Editor-in-Chief of the Journal of Modelling in Management (JM2) and Co-editor-in-Chief of the Innovative Marketing Journal. He has another 4 associate editorships as well as being in the editorial boards of another 47 international academic journals. His areas of research interest encompass marketing and management futurecast, artificial intelligence, biometrics and neuroscience in marketing, futures research algorithmic self, EmoWear - a wearable tech device that detects human emotions, evolutionary algorithms, human-computer interaction, the use of artificial neural networks in marketing, modelling processes of consumer behaviour and tourism futurecast. He has developed a number of conceptual models over the years in areas such as tourism destination decision processes, automated banking, supermarket patronage, among other areas. The testing of these research models has been based on the application of many different statistical, computer and mathematical modelling techniques ranging from multidimensional scaling, multinomial logit generalised linear models (GLMs) and linear structural relations to neural networks, ordered probit, simulated annealing, tabu search, genetic algorithms, memetic algorithms and fuzzy logic. Prof. Moutinho has given keynote speeches, lectures, seminars, talks, etc. in 48 countries worldwide. Prof. Moutinho has 39 books published, over 159 articles published in refereed academic journals. He has 16812 academic citations, the h-index of 59 and the i10-index of 163 (Google Scholar, December 25th, 2023).
Abstract
To investigate the effect of and Acupuncture on brain plasticity and motor development in children with cerebral palsy. Investigate effect on mechanism of apoptosis of brain nerve cells, regulating the expression of neurotrophic factors, promoting the remodeling of
nerve synaptic structure and motor development in young rats with cerebral palsy. Two:To evaluate the effect and mechanism of acupuncture on cerebral palsy. Three:The nerve repair effect of acupuncture on cerebral palsy. Methods: In this study, 146 cases of brain injury and 1078 cases of cerebral palsy were included by randomized controlled study with ICF Gross motor function measure Peabody fine motor function, Gesell, muscle tension, joint activity, activity of daily living transcranial doppler,, skull B ultrasound, Brain Nuclear Magnetic Resonance Imaging MRI, Positron Emission Tomography SPECT, Diffusion tensor tractography evaluation
method. the recovery rate of extracellular space (92.3%) was significantly higher than that of the control group (70.8%) (P <0.05), Transcranial Doppler,TCD total efficiency (79.3%) was significantly higher than that in the control group (51.8%) (P <0.05). Acupuncture to promoting the development of neurological and cognitive movement under 6 months children, effectively reduce the neurological sequelae.The total effective rate of the children with cerebral palsy was 87% in the acupuncture group, which was significantly higher than that of the control group (P <0.01). The total effective rate of Brain MRI was 59.55% in the acupuncture group and 13.25% higher than that in the control group (P <0.01). The total effective rate was 91.3% in the 1 year follow-up group, which was significantly higher than that in the control group (P <0.01). the FA value of white matter fiber bundle was significantly higher than that of acupuncture at 60 times (P <0.05). The recovery rate of ultrasonous brain injury (86.7%) in acupuncture group was significantly higher than that in control group (64.4%) (P <0.05). The recovery rate of brain SPECT in acupuncture group was 96.4%, which was significantly higher than that in the control group (P <0.01). Acupuncture rehabilitation not only promote the development of white matter and gray matter in children with cerebral palsy, but also promote the brain function of children with cerebral palsy remodeling and compensation, and promote social adaptation, language and other cognitive function development, children with cerebral palsy movement and Fine motor function development and recovery, improve the children's self-care ability
Biography
Zhenhuan LIU professor of pediatrics, Pediatric acupuncturist Ph.D. tutor. He has been engaged in pediatric clinical and child rehabilitation for 40 years. Led the rehabilitation team to treat more than 40,000 cases of children with intellectual disability, cerebral palsy and autism from China and more than 20 countries, More than 26800 children's deformity returned to school and society and became self-sufficient. The rehabilitation effect ranks the international advanced level.Vice-chairman of Rehabilitation professional committe children with cerebral palsy, World Federation of Chinese Medicine Societies. Visiting Profassor of Chinese University of Hong Kong in recent 10 years. .He is most famous pediatric neurological and rehabilitation specialists in integrated traditional Chinese and Western medicine in China. He has edited 10 books. He has published 268 papers in international and Chinese medical journals.
Abstract
Proper name anomia is a common experience that can become unpleasantly amplified in people with dementia (PWD). The Gotcha! app aims to provide practice-based therapy for PWD enabling them to spontaneously retrieve the names of key people in their lives. It has been developed using the principles of errorless learning and spaced retrieval pioneered by Clare et al, (2000, 2003), but packaged in an app to support self-management. Gotcha! is a digital confrontation naming therapy app. PWD supply images and names of the people they want to be able to name and train on one face per day for six weeks. We employed a single-case experimental design with weekly testing of free-naming in both six-week blocks (pre therapy and during therapy). A novel speech verifier was used to provide real-time feedback (Barbera et al. 2020). PWD also had an MEG scan before and after the therapy block where they attempt to name pictures of familiar (trained) and famous (untrained) faces. We interrogated the behavioural data in two ways: 1) a within-subject non-parametric analysis using Tau-U metric (Parker et al. 2011); 2) a parametric group analysis using an ANOVA. MEG data were analysed in SPM. We measured source localised gamma-band (30-80 Hz) power 0-1000 ms after the onset of a face. We ran a group-based 2x2 factorial analysis on the resultant images (familiar vs. famous; pre- vs. post-therapy) using a repeated-measures ANOVA to look for changes in power. Results from the MEG analysis of 14 PWD: We identified a large cluster of 813 voxels situated in the left ventral temporal lobe (MNI: -50 -28 -26, F=9.19, p=0.004) where gamma reduction was associated with training (pre-post) of familiar faces, but not (untrained) famous faces. Gotcha! app-based therapy for proper name anomia works for the majority of PWD in our trial thus far. This is the first study to demonstrate that the left ventral temporal lobe region supports practice-based retrieval of familiar face-name associations in PWD. Being able to freely produce the name of a relative or loved one has a big impact on people’s lives.
Biography
I am a PhD candidate at the UCL Queen Square Institute of Neurology, researching Dementia and Alzheimer's within the Brain Repair and Rehabilitation department. My focus is on the Digital interventions in neuro-rehabilitation: neurorehabilitation of people with dementia experiencing difficulty recalling familiar people's names, a specific symptom known as proper name anomia. We are working with people with mild/moderate dementia, including AD/vascular and mixed, primary progressive aphasia, and dementia with Lewy bodies. My research investigating the efficacy of proper name anomia therapy has found evidence that intervention is effective and that behavioral improvements match with changes in the functional language and cognitive networks. Our approach involves a 6-week digital neurorehabilitation therapy delivered through a web-based rehabilitation tool. This tool, co-designed with patients, is currently undergoing phase II clinical trials sponsored by the NIHR. The digital therapy has proven to be an effective alternative to traditional methods, serving a similar purpose as speech-language therapy. Preliminary findings from our research indicate that web-based applications are a promising pathway for implementing scientifically validated behavioral therapies. The goal is to assist individuals with dementia in re-learning the names of important people in their lives. This approach not only enhances their confidence but also creates meaningful communication with their loved ones. I am also conducting Magnetoencephalography (MEG) at the Human Neuroimaging Center at Queen Square on individuals with dementia undergoing the therapy. My focus is on observing the changes in brain activity that arise from the therapeutic interventions. I am doing my research under supervision of Professor Alexandr Leff, the chief investigator of this study. Our goal is to improve our comprehension of neurorehabilitation strategies designed for addressing proper name anomia in peoplew with dementia.
Abstract
Diabetic ketoacidosis (DKA) is a serious, potentially life-threatening complication of diabetes, characterized by hyperglycemia, ketone production, and acidosis. Its neurological impact is profound, particularly in the development of cerebral edema, a dangerous brain swelling associated with DKA. This condition, thought to be triggered by rapid fluid and electrolyte shifts during DKA treatment, highlights the urgency of early DKA detection. Our research is at the forefront of addressing this challenge. We are developing an innovative, non-invasive continuous monitoring system that utilizes advanced biomarkers to identify early signs of DKA. This system promises to revolutionize DKA management by enabling timely intervention, thereby improving patient outcomes and preventing severe neurological complications. Our work underscores the need for innovative approaches in diabetic care and neuroscience. We advocate for continued research in this critical area, aiming to transform diabetes management and mitigate its neurological sequelae.
Biography
Madhini Vigneswaran is completing her undergraduate degree from the School of Biomedical Engineering at the University of British Columbia. She has co-founded a research non-profit organization, MEDIC Foundation, in Canada to research and innovate biomedical solutions for individuals affected by chronic diseases. Additionally, she has co-founded a service non-profit organization, The Global Outreach Project, to donate medical supplies and funds to reduce the gap in access to medical supplies for individuals living in rural communities.
Abstract
The complexities of traumatic brain injury (TBI) delve into the prism of a novel that merges autobiographical and fictional elements, called “The girl of the mental stop”. The protagonist, while describing herself as "a mental mannequin”, reveals a sense of depersonalization. (Torres, 2023, p. 52) Throughout the progression of the disorder, loneliness and estrangement from it emerge as recurring themes, while symptoms suggest an approach to 'madness' before the late diagnosis, delving deeper into the territory of otherness. From this perspective, the thematic dilemmas represented by the self/other, life/death, subject/object relationships are explored, highlighting the disintegration of identity following the impactful "Let me go" (Torres, 2023, p. 136). The narrative strategies express a quest that aligns with the way the experience of illness questions reality itself. The symbolic connection between the woman affected by the invisible illness and the mannequin alludes to the "mental stops", suggesting a connection between the fragmented consciousness and the question of whether meticulous observation of each symptom over the years could have prevented the onset of an irreversible disease. In the mirror, a glimpse of "hidden identity", revealing the reflective action. Appropriation implies the reappropriation of our effort to exist, starting from the initial situation of oblivion. (Ricœur, 1996) In line with psychoanalysis, the research concludes with the affirmation that there is no subject without symptoms (Freud, 1923), opening new perspectives to understand the complexity of traumatic brain injury from a narrative and reflective dimension.
Biography
Laura Torres is currently realizing her PhD in the Department of Medicine and Linguistics, Literature, and Translation at the University of Malaga, UMA, Spain. Her academic journey includes English teaching studies at Maria Inmaculada, CAMMIA, Spain, and earning a master's degree in bilingual teaching from Francisco de Vitoria University in Madrid. Laura served as a teaching assistant in UK during seven years and is actively an English teacher in various Spanish schools since 2017. She is a published author, with a novel titled "The Girl of the Mental Stops, 2023", and has three chapters in scientific books, with a possible potential paper this year.
Abstract
Neurosurgery has undergone a remarkable transformation with the integration of artificial intelligence (AI) technologies, reshaping clinical practice and patient care. This abstract provides an overview of the historical progression of neurosurgery, highlighting the traditional approaches and challenges faced by neurosurgeons before the advent of AI. It then examines the current landscape of neurosurgery infused with AI, elucidating the extent of AI utilization in various facets of neurosurgical practice, including preoperative planning, intraoperative navigation, robotic assistance, predictive analytics, and postoperative care. The advantages of AI in neurosurgery are manifold, encompassing enhanced surgical precision, personalized treatment strategies, improved patient outcomes, and streamlined workflow efficiencies. However, challenges such as data privacy concerns, algorithmic biases, regulatory hurdles, and the need for interdisciplinary collaboration must be addressed to realize the full potential of AI in neurosurgery. Looking ahead, AI holds immense promise for the future of neurosurgery, with advancements in machine learning, neural networks, and computational modelling paving the way for innovative solutions to complex neurosurgical problems. Collaborative efforts between neurosurgeons, data scientists, engineers, and ethicists are essential to harnessing the transformative power of AI and ensuring its responsible integration into neurosurgical practice. By embracing AI-driven innovations, neurosurgeons can navigate challenges with greater confidence, efficacy, and compassion, ultimately advancing the field and improving patient care in neurosurgery.
Biography
Mythili Rajesh, a high school senior, demonstrates a keen interest in neuroscience research and content creation. As a Research Analyst at Neurominds, Mythili has authored insightful blogs on Medium, focusing on various neurological disorders such as Anton’s Syndrome, Parkinsons Disease and so on. Passionate about societal impact, she actively contributes to the dissemination of knowledge. With strong observational, organizational, and communication skills, Mythili excels in collaborative environments. Her dedication to understanding and addressing neurological challenges showcases her commitment to making a positive difference in society.
Abstract
The escalating incidence of stroke-related deaths presents a critical global health challenge. Over recent years, an alarming surge in stroke fatalities has been observed, posing significant burdens on healthcare systems and societies worldwide. This abstract delves into the concerning trend of increasing stroke-related mortality, exploring contributing factors, including lifestyle changes, socioeconomic disparities, and inadequate access to timely and quality healthcare. Understanding the multifaceted reasons behind the rise in stroke-related deaths is imperative for implementing effective interventions and strategies aimed at prevention, early detection, improved treatment modalities, and post-stroke care. Addressing this pressing issue demands urgent collaborative efforts from healthcare providers, policymakers, researchers, and communities to mitigate the devastating impact of strokes on public health.
Biography
Will be updated soon.
Abstract
Will be updated soon.
Biography
Immunologist, Certified Drug Safety Officer for Pharmacovigilance,Clinical Trials Specialist, Monitoring and Medical Writing as well as ICH/GCP. Former Scientific worker and Medical Advisor at Seramun Diagnostica Biotechnology Company in the Department of Research and Development as a Research & Development Scientist as well as Medical Advisor in the field of Immunoassay, Immunodiagnostic, Autoantibody and Autoimmune Diseases. Completed PhD from Charite’-University of Medicine Berlin, Center for Internal Medicine and Dermatology, Internal Medicine Dept. of Rheumatology and Clinical Immunology; German Rheumatology Research Center Berlin; Institute for Immunology, Center for Infection Medicine of Freie University Berlin. Ambassador of Brain City Berlin for Science and Technology. Delegate of Gonder University for international networking with German universities and academic institutions. Ambassador of Tedda Health Science College in Tedda-Gonder Ethiopia. Diaspora Expert for Developing Countries in relation to Health, Education, Research, Capacity Building and Consultation. Co-advisor and lecturer for Master and PhD students & lecturer of undergraduate students in different Ethiopian Universities at Medical Colleges and Faculties. Board Member of Ethiopian Institute of Textile and Fashion Technology EiTEX & Biorefinery Research Center (BRRC of EiTEX) in Bahir Dar University-Ethiopia, Board Member & Founder and General Secretary of Internationale Verein für Gesundheitsförderung in Äthiopien (IVGFÄ) at Germany.Founder & Vice-President of Bridge Ethiopia Network for Science and Technology (BE-NeST) in Germany. Member of German Society for Lupus Research Society/ Deutsche Gesellschaft für Lupus Forschung (DGLF) e,V.in Berlin-Germany. Currently, actively focusing on Global Public Health, Global One Health, International Health Protection against Infection Diseases and Capacity Building in developing Countries.
Abstract
It has been recently shown that nutritional ketosis is effective against seizure disorders and various acute/chronic neurological disorders. Physiologically, glucose is the primary metabolic fuel for cells. However, many neurodegenerative disorders have been associated with impaired glucose transport/metabolism and with mitochondrial dysfunction, such as Alzheimer’s/Parkinson’s disease, general seizure disorders, and traumatic brain injury. Ketone bodies and tricarboxylic acid cycle intermediates represent alternative fuels for the brain and can bypass the ratelimiting steps associated with impaired neuronal glucose metabolism. Therefore, therapeutic ketosis can be considered as a metabolic therapy by providing alternative energy substrates. It has been estimated that the brain derives over 60% of its total energy from ketones when glucose availability is limited. In fact, after prolonged periods of fasting or ketogenic diet (KD), the body utilizes energy obtained from free fatty acids (FFAs) released from adipose tissue. Because the brain is unable to derive significant energy from FFAs, hepatic ketogenesis converts FFAs into ketone bodies-hydroxybutyrate (BHB) and acetoacetate (AcAc)-while a percentage of AcAc spontaneously decarboxylates to acetone. Large quantities of ketone bodies accumulate in the blood through this mechanism. This represents a state of normal physiological ketosis and can be therapeutic. Ketone bodies are transported across the blood-brain barrier by monocarboxylic acid transporters to fuel brain function. Starvation or nutritional ketosis is an essential survival mechanism that ensures metabolic flexibility during prolonged fasting or lack of carbohydrate ingestion. Therapeutic ketosis leads to metabolic adaptations that may improve brain metabolism, restore mitochondrial ATP production, decrease reactive oxygen species production, reduce inflammation, and increase neurotrophic factors’ function. It has been shown that KD mimics the effects of fasting and the lack of glucose/insulin signaling, promoting a metabolic shift towards fatty acid utilization. In this work, the author reports a number of successful case reports treated through metabolic ketosis.
Biography
Raffaele Pilla, Pharm.D., Ph.D., Doctor Europaeus, received his Master’s degree in Pharmacy at G. d’Annunzio University in Chieti-Pescara, Italy in 2005, where he also served internships at the Cell Physiology Laboratory and Molecular Biology Laboratory. Prior, he was an Erasmus Student at Faculté de Pharmacie de Reims in Reims, France. He received his Doctor Europaeus in 2010 from Pitié-Salpétrière Institute in Paris, France. Also in 2010, he received his Ph.D. in Biochemistry, Physiology, and Pathology of Muscle at G. d’Annunzio University in Chieti-Pescara, Italy. He was hired as a Postdoctoral Scholar in the Department of Pharmacology and Physiology at the University of South Florida in Tampa, on two research grants funded by the Office of Naval Research (US Navy) and Divers’ Alert Network. He has written and lectured widely worldwide. He has been involved in ongoing research at the University of South Florida with the use of ketone esters.
“ Will be updated soon...”
“ Will be updated soon...”