Abstract

Objective:To veiify the efficacy of the Psychological Action Rehabilitation on autism treated with Chinese Medicine Music Therapy combined with acupuncture therapy. Methods:A total of 70 cases with autism spectrum disorder (ASD) were divided into an observation group 30 cases and a control group 40 cases.In observation group,the cases were treated with Chinese Medicine Music Therapy combined with acupuncture therapy.The control group was treated with structured education. Clancy Autism Behavior Scale、 Childhood Autism Behavior Scale (CARS)、Autism Behavior Checklist (ABC) and Gesell Development Scale (social adaptive behaviors、personal social behaviors and language development) were adopted to assess the scores before and after treatment.The results were analyzed by SPSS13.0 software. Results:One:During the same time treatment,the observation group’s efficacy on enhancing the intelligence and language ability is apparently better than the control group.Two:In observation,between the group aged from 4to 6 years and the group aged from 2 to 3 years,the differences in Clancy Autism Behavior Scale, ABC and social adaptive development scale are not obvious,which explains that Chinese Medicine Music Therapy combined with acupuncture and therapy can improve autism spectrum disorder children’s behavior and intelligence level regardless of age.Three:As for the scores of language in Gesell scale in the observation group,there were significant differences before and after treatment,which explains that the observation group’s therapy can enhance autism spectrum disorder children’s language skill and is better than the control group’s therapy. Conclusion:Chinese Medicine Music Therapy combined with acupuncture therapy can significantly improve the efficacy on autism spectrum disorder , effectively relieve child autism symptoms and enhance the intelligence and language expression ability . 【Keywords】Autism spectrum disorder; Chinese Medicine Music therapy;Acupuncture.

Biography

Zhenhuan LIU professor of pediatrics,Pediatric acupuncturist Ph.D.tutor.He has been engaged in pediatric clinical and child rehabilitation for 40 years. Led the rehabilitation team to treat more than 40,000 cases of children with intellectual disability, cerebral palsy and autism from China and more than 20 countries,More than 26800 childrens deformity returned to school and society and became self-sufficient.The rehabilitation effect ranks the international advanced level.Vice-chairman of Rehabilitation professional committe children with cerebral palsy,World Federation of Chinese Medicine Societies.Visiting Profassor of Chinese University of Hong Kong in recent 10 years. .He is most famous pediatric neurological and rehabilitation specialists in integrated traditional Chinese and Western medicine in China.He has edited 10 books.He has published 268 papers in international and Chinese medical journals

Abstract

Health problems associated with psychostimulant abuse have become an epidemic. Currently, there are no FDA approved drugs for the management of psychostimulant use disorders, making it increasingly important to identify the mechanisms governing psychostimulant use to advance knowledge related to development of pharmacotherapies. There is evidence that drugs with dual affinity at dopamine transporters (DAT) and sigma-receptors (sigma-R) or combinations of DAT inhibitors (DATi) and sigma-R ligands suppress the consumption and reinforcing effects of psychostimulants (i.e. cocaine). Two identified subtypes of sigma-R, sigma1R and sigma-2R, are thought to play a role in psychostimulant effects, but it is not clear what their comparative roles are in consumption and reinforcing mechanisms. The current consensus is that sigma-1R is more important than sigma-2R; however, we hypothesized that the sigma-2R may play a greater role in suppressing cocaine reinforcement than the sigma-1R. First, a comprehensive review of literature was conducted to understand the comparative roles these two receptors. Next, male Sprague Dawley rats were treated with either (a) rimcazole, (b) methylphenidate + BD 1063 (affinity for sigma-1R > sigma-2R), or (c) methylphenidate + BD 1008 (affinity for sigma-2R > sigma-1R), and the effects on consumption of cocaine when cocaine is freely available was measured. Based on demand curves and models, this research shows that drugs with high affinity for DAT and greater selectivity for sigma-2R than sigma-1R were more effective in suppressing cocaine reinforcement. The implication for the field is that sigma-2R may be more relevant than sigma-1R in the mechanism of cocaine reinforcement

Biography

Roshni Gandhi is a third-year medical student at Cooper Medical School of Rowan University (CMSRU) and graduated with a degree in biomedical engineering from Rowan University in 2021, where she won the DaVinci Medallion for Excellence in Biomedical Engineering. While at CMSRU, she has worked on a number of research projects in clinical medicine encompassing cardiology, internal medicine, surgery, and addiction medicine. She has joined Dr. Martin Job’s research lab where she studies the effects of cocaine on the brain

Abstract

The presentation starts by delving into the areas of behavioural psychology , neuropsychology and Evolutionary psychology. Other topics that follow include neuroscience ,
neuromodulation , genetics , computational neuroscience and behavioural neuroscience . Thetalk will then move on to the discussion of epigenetics and behavioural genetics . Neuro Genetics and Polygenic Risk Scores are also covered . The final part of the presentation is dedicated to the discussion of the concepts like Connectomics , Modular Mind , Neuroimaging Informatics and Open Science .

Biography

Professor Luiz Moutinho (BA, MA, PhD, MAE, FCIM) is a Fellow and Visiting Professor of Marketing at Suffolk Business School, Faculty of Arts, Business and Applied Social Science, University of Suffolk, Ipswich, England, UK, and at The Marketing School, Portugal and Adjunct Professor of Marketing, Graduate School of Business, Faculty of Business and Economics, University of the South Pacific, Suva, Fiji. In 2020 he was elected as the member of The Academia Europaea. In 2017 he received a degree of Prof. Honoris Causa from the Univ. of Tourism and Management Skopje, North Macedonia. During 2015 - 2017 he was professor of BioMarketing and Futures Research at the DCU Business School, Dublin City University, Ireland. This was the first Chair in the world on both domains - BioMarketing and Futures Research. Previously, and for 20 years, he had been appointed as the Foundation Chair of Marketing at the Adam Smith Business School, University of Glasgow, Scotland. Previously, he got his first Chair in 1989 at the University of Wales College of Cardiff 1989-2006. Professor Moutinho completed his PhD at the University of Sheffield in 1982. He has been a Full Professor for 34 years and has held Visiting Professorship positions at numerous universities worldwide. He is the Founding Editor-in-Chief of the Journal of Modelling in Management (JM2) and Co-editor-in-Chief of the Innovative Marketing Journal. His main areas of research interest encompass marketing, management and tourism futurecast, artificial intelligence, biometrics and neuroscience theory, evolutionary algorithms, human-computer interaction, the use of artificial neural networks in marketing, modelling processes of consumer behaviour, futures research. Prof. Moutinho has given keynote speeches, lectures, seminars, talks, etc. in 46 countries worldwide. Prof. Moutinho has 38 books published, over 159 articles published in refereed academic journals. He has 16250 academic citations, the h-index of 59 and the i10-index of 160 (Google Scholar, August 12th, 2023). Professor Luiz Moutinho (BA, MA, PhD, MAE, FCIM) is a Fellow and Visiting Professor of Marketing at Suffolk Business School, Faculty of Arts, Business and Applied Social Science, University of Suffolk, Ipswich, England, UK, and at The Marketing School, Portugal and Adjunct Professor of Marketing, Graduate School of Business, Faculty of Business and Economics, University of the South Pacific, Suva, Fiji. In 2020 he was elected as the member of The Academia Europaea. In 2017 he received a degree of Prof. Honoris Causa from the Univ. of Tourism and Management Skopje, North Macedonia. During 2015 - 2017 he was professor of BioMarketing and Futures Research at the DCU Business School, Dublin City University, Ireland. This was the first Chair in the world on both domains - BioMarketing and Futures Research. Previously, and for 20 years, he had been appointed as the Foundation Chair of Marketing at the Adam Smith Business School, University of Glasgow, Scotland. Previously, he got his first Chair in 1989 at the University of Wales College of Cardiff 1989-2006. Professor Moutinho completed his PhD at the University of Sheffield in 1982. He has been a Full Professor for 34 years and has held Visiting Professorship positions at numerous universities worldwide. He is the Founding Editor-in-Chief of the Journal of Modelling in Management (JM2) and Co-editor-in-Chief of the Innovative Marketing Journal. His main areas of research interest encompass marketing, management and tourism futurecast, artificial intelligence, biometrics and neuroscience theory, evolutionary algorithms, human-computer interaction, the use of artificial neural networks in marketing, modelling processes of consumer behaviour, futures research. Prof. Moutinho has given keynote speeches, lectures, seminars, talks, etc. in 46 countries worldwide. Prof. Moutinho has 38 books published, over 159 articles published in refereed academic journals. He has 16250 academic citations, the h-index of 59 and the i10-index of 160 (Google Scholar, August 12th, 2023).

Abstract

Background: Preclinical research models for phenotypology include categorizing subjects into high versus low takers based on drug intake levels under different contexts. However, because there are many factors that can affect drug intake levels in individuals, it is not clear if these groups represent different phenotypes. We designed experiments to determine if there was consistency in grouping based on intake levels 1) across different doses of cocaine self-administration, and 2) with additional clustering of other behavioral variables in individuals. 

Methods: For male Sprague Dawley rats, we employed median split analysis to classify subjects into high versus low takers across several self-administered cocaine doses (0.00, 0.01, 0.03, 0.1, 0.3, 0.56 and 1.00 mg/kg/infusion). We obtained the inverted U-shaped dose response curve per individual for these cocaine doses and analyzed 1) the structure of the curve using gaussian fit to obtain several variables (peak value, critical point, and width), and 2) the demand curve (with cocaine dose as price) using behavioral economic analysis (exponential function) to obtain consumption at zero price (Q0), demand elasticity/motivation (α) and maximum price (Pmax). We employed normal mixtures clustering analysis/ regression analysis of all the variables to determine if there was more than one cluster of subjects and compared the findings from this analysis to the median split.    

Biography